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Recombinant SH2 domain-containing protein 1A (SH2D1A) 含SH2域蛋白1A(SH2D1A)重組蛋白 貨號:A02036

含SH2域蛋白1A(SH2D1A)重組蛋白

Recombinant SH2 domain-containing protein 1A (SH2D1A)



Recombinant Human SH2 domain-containing protein 1A (SH2D1A)

純度:>85% (SDS-PAGE)

基因名:SH2D1A

Uniprot No.:O60880

別名:DSHP; Duncan disease SH2 protein; Duncan disease SH2-protein; EBVS; IMD5; LYP; MTCP1; SAP; SAP/SH2D1A; SH2 domain containing 1A; SH2 domain protein 1A; SH2 domain-containing protein 1A; SH21A_HUMAN; SH2D1A; Signaling lymphocyte activation molecule associated protein; Signaling lymphocytic activation molecule-associated protein; SLAM associated protein; SLAM associated protein/SH2 domain protein 1A; SLAM-associated protein; T cell signal transduction molecule SAP; T-cell signal transduction molecule SAP; XLP; XLPD

種屬:Homo sapiens (Human)

蛋白長(cháng)度:Partial & Full Length of Mature Protein

來(lái)源:E.coli

產(chǎn)品提供形式:Lyophilized powder & Liquid

儲存條件:Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

功能:Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. Initially it has been proposed that association with SLAMF1 prevents SLAMF1 binding to inhibitory effectors including INPP5D/SHIP1 and PTPN11/SHP-2. However, by simultaneous interactions, recruits FYN which subsequently phosphorylates and activates SLAMF1. Positively regulates CD244/2B4- and CD84-mediated natural killer (NK) cell functions. Can also promote CD48-, SLAMF6 -, LY9-, and SLAMF7-mediated NK cell activation. In the context of NK cell-mediated cytotoxicity enhances conjugate formation with target cells. May also regulate the activity of the neurotrophin receptors NTRK1, NTRK2 and NTRK3.



Recombinant Rat SH2 domain-containing protein 1A (Sh2d1a)

純度:>85% (SDS-PAGE)

基因名:Sh2d1a

Uniprot No.:B2RZ59

別名:Sh2d1a; SH2 domain-containing protein 1A

種屬:Rattus norvegicus (Rat)

蛋白長(cháng)度:Partial & Full Length of Mature Protein

來(lái)源:E.coli

產(chǎn)品提供形式:Lyophilized powder & Liquid

儲存條件:Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

功能:Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. Initially it has been proposed that association with SLAMF1 prevents SLAMF1 binding to inhibitory effectors including INPP5D/SHIP1 and PTPN11/SHP-2. However, by simultaneous interactions, recruits FYN which subsequently phosphorylates and activates SLAMF1. Positively regulates CD244/2B4- and CD84-mediated natural killer (NK) cell functions. Can also promote CD48-, SLAMF6 -, LY9-, and SLAMF7-mediated NK cell activation. In the context of NK cell-mediated cytotoxicity enhances conjugate formation with target cells. May also regulate the activity of the neurotrophin receptors NTRK1, NTRK2 and NTRK3.



Recombinant Mouse SH2 domain-containing protein 1A (Sh2d1a)

純度:>85% (SDS-PAGE)

基因名:Sh2d1a

Uniprot No.:O88890

別名:Sh2d1a; Xlp; SH2 domain-containing protein 1A; Signaling lymphocytic activation molecule-associated protein; SLAM-associated protein; T-cell signal transduction molecule SAP

種屬:Mus musculus (Mouse)

蛋白長(cháng)度:Partial & Full Length of Mature Protein

來(lái)源:E.coli

產(chǎn)品提供形式:Lyophilized powder & Liquid

儲存條件:Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

功能:Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. Initially it has been proposed that association with SLAMF1 prevents SLAMF1 binding to inhibitory effectors including INPP5D/SHIP1 and PTPN11/SHP-2. However, by simultaneous interactions, recruits FYN which subsequently phosphorylates and activates SLAMF1. Positively regulates CD244/2B4- and CD84-mediated natural killer (NK) cell functions. Can also promote CD48-, SLAMF6 -, LY9-, and SLAMF7-mediated NK cell activation. In the context of NK cell-mediated cytotoxicity enhances conjugate formation with target cells. May also regulate the activity of the neurotrophin receptors NTRK1, NTRK2 and NTRK3.






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